Attention is a common but highly complex term associated with a large number of distinct behavioral and perceptual phenomena. In the brain, attention-related changes in neuronal activity are observed in widespread structures. The many distinct behavioral and neuronal phenomena related to attention suggest that it might be subdivided into components corresponding to distinct biological mechanisms. Recent neurophysiological studies in monkeys have isolated behavioral changes related to attention along the 2 indices of signal detection theory and found that these 2 behavioral changes are associated with distinct neuronal changes in different brain areas. These results support the view that attention is made up of distinct neurobiological mechanisms.